FITC标记的核RNA输出因子3抗体
产品名称： FITC标记的核RNA输出因子3抗体
英文名称： Anti-NXF3/FITC
产品编号： HZ--19554R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NXF3/FITC Conjugated antibody
FITC标记的核RNA输出因子3抗体
| 英文名称 | Anti-NXF3/FITC |
| 中文名称 | FITC标记的核RNA输出因子3抗体 |
| 别 名 | Nuclear RNA export factor 3; NXF3; NXF3_HUMAN; OTTHUMP00000023726; OTTHUMP00000023727; TAP like protein 3; TAP-like protein 3; TAPL 3; TAPL-3; TAPL3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 染色质和核信号 转录调节因子 结合蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NXF3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008] Function: May function as a tissue-specific nuclear mRNA export factor. Subcellular Location: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Expressed at high level in testis and at low level in a small number of tissues. Similarity: Belongs to the NXF family. Contains 1 NTF2 domain. Contains 1 RRM (RNA recognition motif) domain. Database links: Entrez Gene: 56000 Human Omim: 300316 Human SwissProt: Q9H4D5 Human Unigene: 60386 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是核RNA输出因子基因家族中的一员。该家族的共同结构域特征是非典型RNP型RNA结合结构域(RBD)、4个富含亮氨酸的重复序列(LRR)、允许与NTF2相关的输出蛋白-1(NXT1)异二聚的核转运因子2(NTF2)样结构域以及介导中间体的泛素相关结构域。具有核孔蛋白的阳离子。LRRS和NTF2类结构域是导出活性所必需的。选择性剪接似乎是一个共同的机制，在这个基因家族。该基因的编码蛋白缩短了LRR和泛素相关结构域，RDB不能与RNA结合。它位于核质中，但与核包膜或核仁无关。[ RefSeq，JUL 2008 ]