FITC标记的鼠抗神经生长因子β单克隆抗体
产品名称： FITC标记的鼠抗神经生长因子β单克隆抗体
英文名称： Anti-NGFB/FITC
产品编号： HZ-10806M-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Mouse Anti-NGFB/FITC Conjugated antibody
FITC标记的鼠抗神经生长因子β单克隆抗体
| 英文名称 | Anti-NGFB/FITC |
| 中文名称 | FITC标记的鼠抗神经生长因子β单克隆抗体 |
| 别 名 | NGF; Beta nerve growth factor; NGF-beta; Beta nerve growth factor precursor; Beta NGF; HSAN5; MGC161426; MGC161428; Nerve growth factor beta; Nerve growth factor beta polypeptide; Nerve growth factor beta subunit; NGF B; NGFB; NID67; NGF beta; NGF-B; NGF_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 发育生物学 神经生物学 细胞因子 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | 3D10 |
| 交叉反应 | Human, Mouse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Recombinded human NGF beta full length protein |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008] Function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Subunit: Homodimer. Subcellular Location: Secreted. Tissue Specificity: Defects in NGF are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. The hereditary sensory and autonomic neuropathies are a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self-mutilation. The autonomic involvement is variable. Similarity: Belongs to the NGF-beta family. Database links:
Entrez Gene: 4803 Human Entrez Gene: 18049 Mouse Entrez Gene: 310738 Rat Omim: 162030 Human SwissProt: P01138 Human SwissProt: P01139 Mouse SwissProt: P25427 Rat Unigene: 2561 Human Unigene: 1259 Mouse Unigene: 22168 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
这个基因是NGF-β家族的成员，并且编码一种分泌蛋白，该蛋白同型化并被结合到一个更大的复合物中。该蛋白具有神经生长刺激活性，该复合物参与调节交感神经和某些感觉神经元的生长和分化。该基因的突变与遗传性感觉和自主神经病变5型（HSAN5）有关，并且该基因表达的失调与变应性鼻炎有关。[ RefSeq，JUL 2008 ]